What is insilicoIDE
insilicoIDE (ISIDE) is an integrated development environment for physiome, i.e. can act as an editor and browser of the multi-level physiological models written in insilicoML (ISML) . ISIDE can import models written in CellML format.
Simulations of the models created by ISIDE can be performed by insilicoSim (ISSim), which is bundled in a ISIDE package available at http://www.physiome.jp/downloads/index.html.
There is another way to run simulations. ISIDE can export C++ and JAVA source codes including numerical integration solvers. Thus users can perform simulations easily by compiling them.
Finite element simulation for partial differential equation based ISML model can be done by exporting FreeFem++ script. Users can perform finite element simulation by running the script.
insilicoIDE ver. 1
The specification of the insilicoML (ISML) is innovated. Now the version of ISML is 1.0. Based upon the upgrade of the ISML specification, we also upgraded the insilicoIDE (ISIDE). There exists a converter from ISML0.1 (previous version) to the ISML1.0, which works with ISIDE ver. 1.
Specifications
insilicoIDE (ISIDE) 1.4 can work on Windows 7, Vista, XP and Mac OS X 10.5, 10.6. Unix like operating systems such as FreeBSD and Linux will be supported soon. ISIDE parses an ISML model with using DOM (Document Object Model) by using APIs written in Python 2.5/2.6. The graphical user interface is built with Qt and C++.
The ISIDE package includes insilicoSim (ISSim), which is a simulator parsing models written in ISML and performing numerical calculations. ISSim can also parse and simulate SBML models and SBML-ISML hybrid models. Regarding the hybrid modeling, please refer the specification of ISML and tutorials. ISSim provides a graphical user interface for easy control of simulations. Besides that the package includes a command-line simulator "isim" which has a capability to perform a parallel computation which is useful for large scale simulations. However, the parallel computing works only on Mac OSX because of library related issues. Please have a look at instructions of isim for more detailed explanation.
Morphology based partial differential equation can be solved by FreeFem++, a open source adaptive finite element method codes, i.e. ISIDE exports an ISML model into the FreeFEM++ format. ISIDE equips a morphology viewer and preprocessing tools, and initial and boundary conditions are set by segmentation assignment visually. Strong form equation is automatically converted to weak form equation.
Downloads
- Latest File Releases
-
- insilicoIDE 1.4.4 for Windows (includes Libraries, model samples and insilicoSim)
- insilicoIDE 1.4.4 for Mac OS X 10.6 (includes Libraries, model samples and insilicoSim)
- insilicoIDE 1.4.4 for Mac OS X 10.5 Intel (includes Libraries, model samples and insilicoSim)
Change log is here.
- Notes
-
- Geometry editor and Segment editor are unified in ver. 1.4.2.
See About_change_of_Morphology_editor.pdf for details. - Supplementary Release Note for ver. 1.3 is here.
- Python APIs are partially sorted out in ver. 1.2. See remark_on_python_apis.txt for details.
- It is strongly recommended to uninstall the older version of ISIDE before installing the new version.
To unistall the older version, run "uninstall.exe" (Windows) or delete the "insilicoPlatform" directory (Mac OS X).
- Geometry editor and Segment editor are unified in ver. 1.4.2.
- Documents
-
- insilicoIDE 1.4 GUI Getting Started -- How to create an ISML model using Model Editor in insilicoIDE
- insilicoIDE 1.4 CLI Getting Started -- How to create an ISML model using insilico terminal in insilicoIDE
- Instructions on insilicoSim -- How to use insilicoSim
- Instructions on isim -- How to use isim
- What is FreeFem++ ? -- Notes for FreeFEM++
- FreeFem++ download information -- FreeFem++ download and installation guide
- Morphology primitives and FreeFem++ functions
- How to Define Morphology Data
- About_change_of_Morphology_editor.pdf
- Segmentation mesh generation and viewing functions
See tutorial for more documents.
- File Releases and Memos
-
insilicoIDE 1.4
Ver. Filename Date Platform Install Memo 1.4.4 insilicoIDE1.4.4.exe 18 Nov. 2011 Windows 7, Vista, XP install_memo_windows.txt 1.4.4 insilicoIDE1.4.4_osx10.6.dmg 18 Nov. 2011 Mac OS X 10.6 install_memo_osx.txt 1.4.4 insilicoIDE1.4.4_osx10.5.dmg 18 Nov. 2011 Mac OS X 10.5 Intel install_memo_osx.txt 1.4.3 insilicoIDE1.4.3.exe 21 Oct. 2011 Windows 7, Vista, XP install_memo_windows.txt 1.4.3 insilicoIDE1.4.3_osx10.6.dmg 21 Oct. 2011 Mac OS X 10.6 install_memo_osx.txt 1.4.3 insilicoIDE1.4.3_osx10.5.dmg 21 Oct. 2011 Mac OS X 10.5 Intel install_memo_osx.txt 1.4.2 insilicoIDE1.4.2.exe 12 Sep. 2011 Windows 7, Vista, XP install_memo_windows.txt 1.4.2 insilicoIDE1.4.2_osx10.6.dmg 12 Sep. 2011 Mac OS X 10.6 install_memo_osx.txt 1.4.2 insilicoIDE1.4.2_osx10.5.dmg 12 Sep. 2011 Mac OS X 10.5 Intel install_memo_osx.txt 1.4.1 insilicoIDE1.4.1.exe 19 Jul. 2011 Windows 7, Vista, XP install_memo_windows.txt 1.4.1 insilicoIDE1.4.1_osx10.6.dmg 19 Jul. 2011 Mac OS X 10.6 install_memo_osx.txt 1.4.1 insilicoIDE1.4.1_osx10.5.dmg 19 Jul. 2011 Mac OS X 10.5 Intel install_memo_osx.txt 1.4.0.2 insilicoIDE1.4.0.2.exe 10 Jun. 2011 Windows 7, Vista, XP install_memo_windows.txt 1.4.0.2 insilicoIDE1.4.0.2_osx10.6.dmg 10 Jun. 2011 Mac OS X 10.6 install_memo_osx.txt 1.4.0.2 insilicoIDE1.4.0.2_osx10.5.dmg 10 Jun. 2011 Mac OS X 10.5 Intel install_memo_osx.txt 1.4.0.1 insilicoIDE1.4.0.1.exe 20 May 2011 Windows 7, Vista, XP install_memo_windows.txt 1.4.0.1 insilicoIDE1.4.0.1_osx10.6.dmg 20 May 2011 Mac OS X 10.6 install_memo_osx.txt 1.4.0.1 insilicoIDE1.4.0.1_osx10.5.dmg 20 May 2011 Mac OS X 10.5 Intel install_memo_osx.txt 1.4.0 insilicoIDE1.4.0.exe 28 Apr. 2011 Windows 7, Vista, XP install_memo_windows.txt 1.4.0 insilicoIDE1.4.0_osx10.6.dmg 28 Apr. 2011 Mac OS X 10.6 install_memo_osx.txt 1.4.0 insilicoIDE1.4.0_osx10.5.dmg 28 Apr. 2011 Mac OS X 10.5 Intel install_memo_osx.txt insilicoIDE 1.3
Ver. Filename Date Platform Install Memo 1.3.3 insilicoIDE1.3.3.exe 10 Feb. 2011 Windows XP, 2000 install_memo_windows.txt 1.3.3 insilicoIDE1.3.3_osx10.6.dmg 10 Feb. 2011 Mac OS X 10.6 install_memo_osx.txt 1.3.3 insilicoIDE1.3.3_osx10.5.dmg 10 Feb. 2011 Mac OS X 10.5 Intel install_memo_osx.txt 1.3.2 insilicoIDE1.3.2.exe 28 Dec. 2010 Windows XP, 2000 install_memo_windows.txt 1.3.2 insilicoIDE1.3.2_osx10.6.dmg 28 Dec. 2010 Mac OS X 10.6 install_memo_osx.txt 1.3.2 insilicoIDE1.3.2_osx10.5.dmg 28 Dec. 2010 Mac OS X 10.5 Intel install_memo_osx.txt 1.3.1 insilicoIDE1.3.1.exe 06 Oct. 2010 Windows XP, 2000 install_memo_windows.txt 1.3.1 insilicoIDE1.3.1_osx10.6.dmg 06 Oct. 2010 Mac OS X 10.6 install_memo_osx.txt 1.3.1 insilicoIDE1.3.1_osx10.5.dmg 06 Oct. 2010 Mac OS X 10.5 Intel install_memo_osx.txt 1.3.0 insilicoIDE1.3.0.exe 01 Sep. 2010 Windows XP, 2000 install_memo_windows.txt 1.3.0 insilicoIDE1.3.0_osx10.6.dmg 01 Sep. 2010 Mac OS X 10.6 install_memo_osx.txt 1.3.0 insilicoIDE1.3.0_osx10.5.dmg 01 Sep. 2010 Mac OS X 10.5 Intel install_memo_osx.txt insilicoIDE 1.2
Ver. Filename Date Platform Install Memo 1.2.1 insilicoIDE1.2.1.exe 20 Jul. 2010 Windows XP, 2000 install_memo_windows.txt 1.2.1 insilicoIDE1.2.1_osx10.6.dmg 20 Jul. 2010 Mac OS X 10.6 install_memo_osx.txt 1.2.1 insilicoIDE1.2.1_osx10.5.dmg 20 Jul. 2010 Mac OS X 10.5 Intel install_memo_osx.txt 1.2.1 sample.zip 20 Jul. 2010 - only sample models 1.2.0 insilicoIDE1.2.0.exe 25 Jun. 2010 Windows XP, 2000 install_memo_windows.txt 1.2.0 insilicoIDE1.2.0_osx10.6.dmg 25 Jun. 2010 Mac OS X 10.6 install_memo_osx.txt 1.2.0 insilicoIDE1.2.0_osx10.5.dmg 25 Jun. 2010 Mac OS X 10.5 Intel install_memo_osx.txt insilicoIDE 1.1
Ver. Filename Date Platform Install Memo 1.1.2 insilicoIDE1.1.2.exe 31 Mar. 2010 Windows XP, 2000 - 1.1.2 insilicoIDE1.1.2_osx10.6.dmg 31 Mar. 2010 Mac OS X 10.6 install_memo_osx.txt 1.1.2 insilicoIDE1.1.2_osx10.5.dmg 31 Mar. 2010 Mac OS X 10.5 Intel install_memo_osx.txt 1.1.1 insilicoIDE1.1.1.exe 05 Mar. 2010 Windows XP, 2000 - 1.1.1 insilicoIDE1.1.1_osx10.6.dmg 05 Mar. 2010 Mac OS X 10.6 install_memo_osx.txt 1.1.1 insilicoIDE1.1.1_osx10.5.dmg 05 Mar. 2010 Mac OS X 10.5 Intel install_memo_osx.txt 1.1.0 insilicoIDE1.1.0.exe 16 Feb. 2010 Windows XP, 2000 - 1.1.0 insilicoIDE1.1.0_osx10.6.dmg 16 Feb. 2010 Mac OS X 10.6 install_memo_osx.txt 1.1.0 insilicoIDE1.1.0_osx10.5.dmg 16 Feb. 2010 Mac OS X 10.5 Intel install_memo_osx.txt insilicoIDE 1.0
Ver. Filename Date Platform Install Memo 1.0.4 insilicoIDE1.0.4.exe 15 Jan. 2010 Windows XP, 2000 install_memo_windows.txt 1.0.4 insilicoIDE1.0.4_osx10.6.dmg 15 Jan. 2010 Mac OS X 10.6 install_memo_osx.txt 1.0.4 insilicoIDE1.0.4_osx10.5.dmg 15 Jan. 2010 Mac OS X 10.5 Intel install_memo_osx.txt 1.0.3 insilicoIDE1.0.3.exe 8 Jan. 2010 Windows XP, 2000 install_memo_windows.txt 1.0.3 insilicoIDE1.0.3_osx10.6.dmg 13 Jan. 2010 Mac OS X 10.6 install_memo_osx.txt 1.0.3 insilicoIDE1.0.3_osx10.5.dmg 13 Jan. 2010 Mac OS X 10.5 Intel install_memo_osx.txt 1.0.2 insilicoIDE1.0.2.zip 30 Nov. 2009 Windows XP, 2000 install_memo_windows.txt 1.0.2 insilicoIDE1.0.2.tar.gz 30 Nov. 2009 Mac OS X 10.5 Intel - 1.0.0b insilicoIDE1.0.0b_win.zip 13 Oct. 2009 Windows XP, 2000 install_memo_windows.txt 1.0.0b insilicoIDE1.0.0b.pkg 13 Oct. 2009 Mac OS X 10.5 Intel - insilicoIDE 0.3
Ver. Filename Date Platform How to Install User Manual 0.3.1 insilicoIDEsetup.exe 26 Feb. 2009 Windows XP, 2000 howtoinstall_0.3.1.html readme_getting_started.pdf 0.3.1 insilicoIDE0.3.1.zip 26 Feb. 2009 Windows XP, 2000 howtoinstall_0.3.1.html readme_getting_started.pdf 0.3.0 insilicoIDEsetup.exe 06 Feb. 2009 Windows XP, 2000 howtoinstall_0.3.html readme_getting_started.pdf insilicoIDE 0.2
Ver. Filename Date Platform How to Install User Manual 0.2.6 insilicoIDE0.2.6.zip 16 Dec. 2008 Windows XP, 2000 howtoinstall_0.2.html gettingstarted_0.2.5-1.html 0.2.5 insilicoIDE0.2.5.zip 20 Oct. 2008 Windows XP, 2000 howtoinstall_0.2.html gettingstarted_0.2.5-1.html 0.2.4 insilicoIDE0.2.4.zip 18 Sep. 2008 Windows XP, 2000 howtoinstall_0.2.html gettingstarted_0.2-1.html 0.2.3 insilicoIDE0.2.3.zip 11 Sep. 2008 Windows XP, 2000 howtoinstall_0.2.html gettingstarted_0.2-1.html 0.2.2 insilicoIDE0.2.2.zip 03 Sep. 2008 Windows XP, 2000 howtoinstall_0.2.html gettingstarted_0.2-1.html 0.2.1 insilicoIDE0.2.1.zip 11 Aug. 2008 Windows XP, 2000 howtoinstall_0.2.html gettingstarted_0.2-1.html 0.2.0 insilicoIDE0.2.zip 15 Jul. 2008 Windows XP, 2000 howtoinstall_0.2.html gettingstarted_0.2-1.html insilicoIDE 0.1
Ver. Filename Date Platform How to Install User Manual 0.1.1 insilicoIDE0.1.1.zip 20 Jun. 2008 Windows XP, 2000 howtoinstall_0.1.1.html gettingstarted_0.1.1-1.html 0.1.1 insilicoIDE 0.1.1pg.zip 20 Jun. 2008 Windows XP, 2000 howtoinstall_0.1.1.html gettingstarted_0.1.1-1.html 0.1.0 insilicoIDE0.1.zip 21 May 2008 Windows XP, 2000 howtoinstall_0.1.0.html gettingstarted_0.1.0-1.html 0.1.0 insilicoIDE 0.1.0.pg.zip 21 May 2008 Windows XP, 2000 howtoinstall_0.1.0.html gettingstarted_0.1.0-1.html







